I would lean Jackson vs. NE, as the offense runs through the Rbs in Buf.
As for your flex....yuck. Stevie is nursing an injury, but Crabtree hasn't been all that. This may be the ultimate toss up. I would probably lean Crabtree.
With rumors that Brown will play tonight I too would say Fast Freddie and Johnson banged up would force me to go with Crabs as well. I do think the Bills are about to lean on Spiller more but Fred will get his chances.